VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Cat

Scientific Name: Felis catus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Carnivora-> Feliformia-> Felidae

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Bovine alphaherpesvirus 1

Family: Herpesviridae

Receptor: NECTIN1

Receptor NECTIN1 information

Summary: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0028 2021.04 10X Genomics Esophagus Normal 1928 Link
Vthunter_0029 2021.04 10X Genomics Eyelid Normal 679 Link
Vthunter_0030 2021.04 10X Genomics Heart Normal 8209 Link
Vthunter_0031 2021.04 10X Genomics Kidney Normal 2831 Link
Vthunter_0032 2021.04 10X Genomics Liver Normal 7889 Link
Vthunter_0033 2021.04 10X Genomics Lung Normal 8591 Link
Vthunter_0034 2021.04 10X Genomics Rectum Normal 1503 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of NECTIN1 in human tissues   [NCBI]

Expression: Biased expression in skin (RPKM 64.2), esophagus (RPKM 38.3) and 8 other tissues

Protein expression of NECTIN1 in human tissues   [Proteinatlas]